UNITOV: Design of nature-inspired strategies to control DNA-based responsive units

In this project, we will be aiming to:

i) Rationally design nature-inspired strategies (allostery, cooperativity, feedback mechanism, amplification, etc) to finely control the signalling of DNA-based responsive units

ii) Achieve control over the input/output behaviour of the responsive units (digital-like response, extended dynamic range response, amplified signalling etc).


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