UNITOV: Design and characterization of DNA-based responsive units

Lorena Baranda will be working in Francesco Ricci’s lab to:

i) Develop DNA-based functional responsive units that undergo binding-induced conformational changes in the presence of specific molecular cues (i.e. small molecules, enzymes, antibodies etc) or in response to environmental (i.e. pH, temperature) or electrochemical stimuli

ii) Characterize the thermodynamic of the responsive units using both optical and electrochemical labels; iii) Demonstrate the use of responsive units for sensing and diagnostic applications.


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