Application deadline has been exceeded.

The project will be conducted in the research group of Professor Kurt Vesterager Gothelf at the Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry.

Research area and project description:

The purpose of the PhD project is to design and explore methods for signal-transfer in and between DNA nanostructures. The candidate will use computer aided design programs to design DNA origami structures and invent DNA-based signal transfer reactions such as e.g. the hybridization chain reaction to transfer signals across the structure. Furthermore, the candidate will design interface mechanisms between the signalling system and sensor and/or actuator modules. The structures will be made by self-assembly of DNA structures and their structure and dynamics will be analysed by the candidate by atomic force microscopy, transmission electron microscopy, optical methods and other biophysical techniques.

The position is for 3 years and is funded by the PhD school DNA-Robotics, a recently established Innovative Training Network (ITN) under the European Commission’s Marie Skłodowska-Curie Actions research fellowship programme. DNA-Robotics (DNABOT) will foster the development of a new generation of scientists with the skills required to meet futures challenges in bionanotechnology, from fundamental science to novel applications. The PhD study involve 3 months of secondments in total at one or more of the other partner universities in the network.

Qualifications and specific competences:

The successful candidate should have completed a master’s degree (or equivalent) in chemistry, molecular biology, physics, computer science or related disciplines no later than August 1, 2018. The candidate should have laboratory experience within experimental chemistry, biophysics, or molecular biology. Furthermore, the candidate should be interested in and qualified to use software tools for advanced structure design and for making illustrations by 3D rendering. To qualify for funding under the rules of the Marie Skłodowska-Curie action, candidates must: i) not have lived in Denmark for more than 12 months in the last 3 years ii) not already possess a PhD degree and iii) be in the first four years of their research career, since, for example, completion of a masters’ degree.