In this article we show two different approaches to produce linear actuators made from DNA
In all levels of engineering, complex machinery is based on the concerted activity of many different subunits of heterogeneous nature. One of such subunits are the linear actuators we refer to in the title. Basically, a linear actuator is a device or construct capable of producing a motion confined in one axis; this type of devices, as they are currently found in mechanisms and machines, can be as large as the ones found in the hydraulic arm of an excavator or as precise as the piezoelectric actuators capable of movements in the nanometer range.
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In this work we demonstrated how to repurpose IgG antibodies to boost different chemical reactions and synthesize functional molecules.
The work has recently been published in Nature Communications. Follow this link to read the full article or read Lorena’s post below for a summary.
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Analysing coarse-grained simulations of DNA and RNA nanostructures is now much easier. With the new oxView tool published by the Šulc lab, oxDNA simulations are now more accessible to experimental groups, allowing for iterative design and evaluation of structures.
The article has been published in the journal Nucleic Acid Research. Follow this link to read the full article or read Joakim’s post below for a shorter version.
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