From small molecules to biological polymers, the dance between organic synthesis and biochemistry

Hey, my name is Angel and I would like to explain a bit about bio-conjugation in the space between organic synthesis and biochemistry

The perspective for nano-sized DNA robots

This articles aims to explain the basic concepts, perspectives and the main ethical considerations regarding the concept of DNA nano-robots. This outreach paper has been written with equal contributions from all the DNA-Robotics Early stage researches. Authors are listed in random order:

Quentin Vincentini, Lorena Baranda Pellejero, Aitor Patiño Díaz, Alba Monferrer i Sureda, Michael Pinner, Yash Bogawat, Minke Nijenhuis, Angel Santorelli, Nestor Sampedro, Marco Llocaico, Igor Baars, Mihir Dass, Karol Kolataj, Joakim Bohlin, Rafael Carrascosa Marzo.

The death of the author

“A text’s unity lies not in its origin, but in its destination.” – Roland Barthes (1967, translated 1977)

I am in the middle of writing my PhD thesis. This is generally not considered an easy process, and I concur with that sentiment. For me, it includes stretches of intense productivity, digging for long-forgotten data, and dry eyes. There are also long periods of staring out of the window, while stewing on my thoughts. In one such stewing session, my thoughts wandered towards the quote above. It is from the essay “The Death of the Author” by Roland Barthes. Barthes disapproved of the idea that to find the true meaning of a text, one must consider it through the identity of its scripter. Instead, he argued that meaning lies exclusively in the words themselves, and their impressions on the reader. Thus, the unity of a text is not found in its origin, but in its destination. As Barthes wrote himself, “writing is that into which every subject escapes, the trap where all identity is lost, beginning with the very identity of the body that writes.”1 “The author enters into their own death, and writing begins.”2

DNA nanotechnologies: ideal tools for theranostics?

Theranostics is an emerging field that combines the power of diagnostics and therapeutic at the same time. The idea is not completely new, Nuclear Medicine has been using for example radioactive iodine to both image and treat certain types of thyroidal diseases (1), but nanotechnologies have the potential to generate highly controllable systems and expand the therapeutic arsenal of clinicians.