This is the pre-peer reviewed version of the following article: Protein-Templated Reactions Using DNA-Antibody Conjugates, which has been published in final form at https://doi.org/10.1002/smll.202200971. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
“This document is the unedited Author’s version of a Submitted Work that was subsequently accepted for publication in ACS Sensors, copyright © [include copyright notice from the published article] after peer review. To access the final edited and published work see https://pubs.acs.org/doi/10.1021/acssensors.1c02642
In this article published in ACS NANO, a DNA origami structure is shown capable of clustering DR5. When this cluster inducing origami is added to cancer cells, it is shown to cause apoptosis and cell death. As much as 80% of some cell types went into apoptosis with one version of this DNA origami structure.
Hey, my name is Angel and I would like to explain a bit about bio-conjugation in the space between organic synthesis and biochemistry
Hi there, Alba here! I will use today’s online lecture as an opportunity to explain to you how we in Dietz lab have created a DNA origami platform for virus trapping.